The Human Phenotype Ontology (HPO) provides a standardized vocabulary of phenotypic abnormalities encountered in human disease. Each term in the HPO describes a phenotypic abnormality in order to be used to support differential diagnostics, translational research, and a number of applications in computational biology by providing the means to compute over the clinical phenotype.
Morever, this ontology is being increasingly adopted as a standard for phenotypic abnormalities by diverse groups such as international rare disease organizations, registries or clinical labs, allowing the interoperability of data among different sources and thus contributing to global data exchange for identifying disease etiologies.
The HPO is a flagship product of the Monarch Initiative, an NIH-supported international consortium dedicated to semantic integration of biomedical and model organism data with the ultimate goal of improving biomedical research.
A new version to date September 2019 has just been released! Find in the HPO website all the information of this ontology including the most updated version!