Contact us   |  

Animal models of TTP

Animal models of TTP

31/03/2021 16:00

Speakers: Karen Vanhoorelbeke

Target: Health professionals
Subnetworks: Bleeding - Coagulation disorders
Disease Groups: Rare thrombotic disorder due to quantitative platelet anomaly (Low)

Karen Vanhoorelbeke, PhD, is since 2007 professor at KU Leuven, Campus Kulak, Kortrijk, Belgium, where she is principle investigator at the Laboratory for Thrombosis Research and chairman of the Interdisciplinary Research Facility. In 2010 she worked in the lab of prof. dr. Tim Springer at Harvard Medical School, Boston as a visiting professor.

Her research focuses on the molecular mechanisms by which the hemostatic proteins van Willebrand factor (VWF) and its cleaving enzyme ADAMTS13 contribute to health and disease. Her group performs fundamental research to understand the role of VWF and ADAMTS13 in hemostasis, bleeding and thrombosis and to unravel their mode-of-action. These findings form the basis for translational research lines where preclinical animal models are established to study disease pathology and new treatment strategies.

Her research is embedded in several national and international research projects. Recently she was awarded a Horizon2020 Marie Curie training network grant 'PROFILE' of which she is the coordinator. She is author and coauthor of more than 160 scientific publications in international peer reviewed journals and is (co) promotor of 30 PhD students.