Departments

About the department

Department name (English): Clinical Haematology

Department name (original): Hematologia Clínica

Subnetworks of expertise:

• Myeloid malignancies
• Lymphoid malignancies
• Bleeding - Coagulation disorders
• Hemochromatosis and other iron disorders

Healthcare provider: Centro Hospitalar Universitário de Santo António

Diseases covered by the department:

• Tumor of hematopoietic and lymphoid tissues
• Mastocytosis
• Systemic mastocytosis
• Indolent systemic mastocytosis
• Smouldering systemic mastocytosis
• Isolated bone marrow mastocytosis
• Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease
• Aggressive systemic mastocytosis
• Lymphoadenopathic mastocytosis with eosinophilia
• Mast cell leukemia
• Classic mast cell leukemia
• Aleukemic mast cell leukemia
• Cutaneous mastocytosis
• Cutaneous mastocytoma
• Diffuse cutaneous mastocytosis
• Bullous diffuse cutaneous mastocytosis
• Pseudoxanthomatous diffuse cutaneous mastocytosis
• Maculopapular cutaneous mastocytosis
• Telangiectasia macularis eruptiva perstans
• Typical urticaria pigmentosa
• Plaque-form urticaria pigmentosa
• Nodular urticaria pigmentosa
• Mast cell sarcoma
• Extracutaneous mastocytoma
• Essential thrombocythemia
• Hereditary thrombocytopenia with early-onset myelofibrosis
• Gaisböck syndrome
• Rare coagulation disorder
• Rare thrombotic disease of hematologic origin
• Rare thrombotic disorder due to a coagulation factors defect
• Rare thrombotic disorder due to a constitutional coagulation factors defect
• Congenital factor XII deficiency
• Familial thrombomodulin anomalies
• Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency
• Rare hereditary thrombophilia
• Hereditary thrombophilia due to congenital protein S deficiency
• Hereditary thrombophilia due to congenital protein C deficiency
• Hereditary thrombophilia due to congenital antithrombin deficiency
• Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency
• Rare thrombotic disorder due to an acquired coagulation factors defect
• Catastrophic antiphospholipid syndrome
• Heparin-induced thrombocytopenia
• Protein S acquired deficiency
• Acquired purpura fulminans
• Simple cryoglobulinemia
• Rare thrombotic disorder due to a platelet anomaly
• Thrombotic thrombocytopenic purpura
• Congenital thrombotic thrombocytopenic purpura
• Acquired thrombotic thrombocytopenic purpura
• Rare thrombotic disorder due to a constitutional platelet anomaly
• Familial thrombocytosis
• Hereditary thrombocytosis with transverse limb defect
• Rare thrombotic disorder due to an acquired platelet anomaly
• Rare hemorrhagic disorder
• Rare hemorrhagic disorder due to a coagulation factors defect
• Rare hemorrhagic disorder due to a constitutional coagulation factors defect
• Multiple sclerosis-ichthyosis-factor VIII deficiency syndrome
• Hemophilia
• Hemophilia A
• Severe hemophilia A
• Moderately severe hemophilia A
• Mild hemophilia A
• Symptomatic form of hemophilia A in female carriers
• Hemophilia B
• Severe hemophilia B
• Moderately severe hemophilia B
• Mild hemophilia B
• Symptomatic form of hemophilia B in female carriers
• Congenital factor V deficiency
• Congenital fibrinogen deficiency
• Familial afibrinogenemia
• Familial dysfibrinogenemia
• Familial hypofibrinogenemia
• Familial hypodysfibrinogenemia
• Congenital alpha2-antiplasmin deficiency
• Congenital factor XIII deficiency
• Von Willebrand disease
• Von Willebrand disease type 1
• Von Willebrand disease type 2
• Von Willebrand disease type 2A
• Von Willebrand disease type 2B
• Von Willebrand disease type 2M
• Von Willebrand disease type 2N
• Von Willebrand disease type 3
• Congenital factor XI deficiency
• Congenital plasminogen activator inhibitor type 1 deficiency
• Congenital high-molecular-weight kininogen deficiency
• Congenital prekallikrein deficiency
• Combined deficiency of factor V and factor VIII
• Congenital vitamin K-dependent coagulation factors deficiency
• Congenital factor VII deficiency
• Congenital factor II deficiency
• Congenital factor X deficiency
• Hereditary combined deficiency of vitamin K-dependent clotting factors
• Hemorrhagic disease due to alpha-1-antitrypsin Pittsburgh mutation
• East Texas bleeding disorder
• Thrombomodulin-related bleeding disorder
• Rare hemorrhagic disorder due to an acquired coagulation factor defect
• Acquired prothrombin deficiency
• Acquired hemophilia
• Acquired von Willebrand syndrome
• Rare hemorrhagic disorder due to a platelet anomaly
• Rare hemorrhagic disorder due to a constitutional platelet anomaly
• Rare hemorrhagic disorder due to a constitutional thrombocytopenia
• Syndromic constitutional thrombocytopenia
• Stormorken-Sjaastad-Langslet syndrome
• Thrombocytopenia-absent radius syndrome
• Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome
• MYH9-related disease
• GNE myopathy
• Jacobsen syndrome
• Macrothrombocytopenia with mitral valve insufficiency
• Alpha delta granule deficiency
• Dense granule disease
• Wiskott-Aldrich syndrome
• Chédiak-Higashi syndrome
• Hereditary thrombocytopenia with normal platelets-hematological cancer predisposition syndrome
• Hermansky-Pudlak syndrome
• Hermansky-Pudlak syndrome with neutropenia
• Hermansky-Pudlak syndrome with pulmonary fibrosis
• Hermansky-Pudlak syndrome without pulmonary fibrosis
• Hermansky-Pudlak syndrome type 7
• Hermansky-Pudlak syndrome type 8
• Hermansky-Pudlak syndrome type 9
• Isolated constitutional thrombocytopenia
• Isolated hereditary giant platelet disorder
• Severe autosomal recessive macrothrombocytopenia
• Bernard-Soulier syndrome
• Thrombocytopenia with congenital dyserythropoietic anemia
• Autosomal dominant macrothrombocytopenia
• Alpha granule disease
• Gray platelet syndrome
• Quebec platelet disorder
• Medich giant platelet syndrome
• White platelet syndrome
• Paris-Trousseau thrombocytopenia
• X-linked dyserythropoetic anemia with abnormal platelets and neutropenia
• Hereditary thrombocytopenia with normal platelets
• X-linked thrombocytopenia with normal platelets
• Autosomal thrombocytopenia with normal platelets
• Congenital amegakaryocytic thrombocytopenia
• Bleeding diathesis due to thromboxane synthesis deficiency
• Isolated delta-storage pool disease
• Autosomal dominant thrombocytopenia with platelet secretion defect
• Rare hemorrhagic disorder due to a qualitative platelet defect
• Glanzmann thrombasthenia
• Cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder
• Ehlers-Danlos syndrome, fibronectinemic type
• Scott syndrome
• P2Y12 defect
• Pseudo-von Willebrand disease
• Bleeding diathesis due to a collagen receptor defect
• Bleeding diathesis due to glycoprotein VI deficiency
• Bleeding diathesis due to integrin alpha2-beta1 deficiency
• Bleeding disorder due to CalDAG-GEFI deficiency
• Rare hemorrhagic disorder due to an acquired platelet anomaly
• Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome
• TAFRO syndrome
• HELLP syndrome
• Fetal and neonatal alloimmune thrombocytopenia
• Autoimmune thrombocytopenia
• Immune thrombocytopenic purpura
• Evans syndrome
• STAT3-related early-onset multisystem autoimmune disease
• Kasabach-Merritt syndrome
• Rare anemia
• Rare deficiency anemia
• Rare hereditary hemochromatosis
• HFE related hereditary hemochromatosis (Symptomatic form of hemochromatosis type 1) - OMIM 235200
• HJV related hereditary hemochromatosis - OMIM 602390 (Hemochromatosis type 2A)
• HAMP related hereditary hemochromatosis - OMIM 613313 (Hemochromatosis type 2B)
• TFR2 related hereditary hemochromatosis OMIM 604250 (Hemochromatosis type 3)
• FTH related hereditary hemochromatosis - OMIM 615517 (Hemochromatosis type 5)
• Ferroportin Disease (Hemochromatosis type 4B)​
• SLC40A1 related hereditary hemochromatosis - OMIM 606069 (Hemochromatosis type 4A)
• Rare iron overload
• Rare Ferritinopathy

Service offered

• Prevention and genetic counseling
• Diagnostics
• Treatment and care

Patients covered

• Pediatrics
• Adults
• Ageing