Departments

About the department

Department name (English): Pediatric Hematology and Oncology

Department name (original): Hematología y Oncología pediátrica

Subnetworks of expertise:

• Myeloid malignancies
• Lymphoid malignancies
• Bleeding - Coagulation disorders
• Red blood cell defects
• Bone marrow failure

Healthcare provider: Hospital General Universitario Gregorio Marañón

Diseases covered by the department:

• Tumor of hematopoietic and lymphoid tissues
• Bloom syndrome
• Deafness-lymphedema-leukemia syndrome
• Mastocytosis
• Systemic mastocytosis
• Indolent systemic mastocytosis
• Smouldering systemic mastocytosis
• Isolated bone marrow mastocytosis
• Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease
• Aggressive systemic mastocytosis
• Lymphoadenopathic mastocytosis with eosinophilia
• Mast cell leukemia
• Classic mast cell leukemia
• Aleukemic mast cell leukemia
• Cutaneous mastocytosis
• Cutaneous mastocytoma
• Diffuse cutaneous mastocytosis
• Bullous diffuse cutaneous mastocytosis
• Pseudoxanthomatous diffuse cutaneous mastocytosis
• Maculopapular cutaneous mastocytosis
• Telangiectasia macularis eruptiva perstans
• Typical urticaria pigmentosa
• Plaque-form urticaria pigmentosa
• Nodular urticaria pigmentosa
• Mast cell sarcoma
• Extracutaneous mastocytoma
• Myeloid hemopathy
• Acute myeloid leukemia
• Acute myeloid leukemia with multilineage dysplasia
• Therapy related acute myeloid leukemia and myelodysplastic syndrome
• Acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent
• Acute myeloid leukemia and myelodysplastic syndromes related to topoisomerase type 2 inhibitor
• Acute myeloid leukemia and myelodysplastic syndromes related to radiation
• Acute leukemia of ambiguous lineage
• Acute undifferentiated leukemia
• Bilineal acute leukemia
• Acute biphenotypic leukemia
• Acute myeloid leukemia with recurrent genetic anomaly
• Acute promyelocytic leukemia
• Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
• Acute myeloid leukemia with 11q23 abnormalities
• Acute myeloid leukemia with t(8;21)(q22;q22) translocation
• Acute myeloid leukemia with CEBPA somatic mutations
• Acute myeloid leukemia with t(8;16)(p11;p13) translocation
• Acute myeloid leukemia with t(6;9)(p23;q34)
• Acute myeloid leukemia with t(9;11)(p22;q23)
• Acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)
• Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)
• Acute myeloid leukemia with NPM1 somatic mutations
• Unclassified acute myeloid leukemia
• Acute erythroid leukemia
• Acute megakaryoblastic leukemia
• Acute megakaryoblastic leukemia in Down syndrome
• Acute megakaryoblastic leukemia without Down syndrome
• Acute panmyelosis with myelofibrosis
• Acute basophilic leukemia
• Myeloid sarcoma
• Acute myeloid leukemia with minimal differentiation
• Acute myeloblastic leukemia without maturation
• Acute myeloblastic leukemia with maturation
• Acute myelomonocytic leukemia
• Acute monoblastic leukemia
• Inherited acute myeloid leukemia
• Inherited acute myeloid leukemia with presdisposing GAT2 mutation
• Inherited acute myeloid leukemia with presdisposing RUNX1 mutation
• Inherited acute myeloid leukemia with presdisposing DDX41 mutation
• Myelodysplastic syndrome
• Acquired idiopathic sideroblastic anemia
• Refractory cytopenia with multilineage dysplasia
• Refractory anemia
• Unclassified myelodysplastic syndrome
• Aregenerative anemia
• Refractory anemia with excess blasts
• Refractory anemia with excess blasts type 1
• Refractory anemia with excess blasts type 2
• Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality
• Refractory anemia with excess blasts in transformation
• Myeloproliferative neoplasm
• Essential thrombocythemia
• Chronic myeloid leukemia
• Primary myelofibrosis
• Polycythemia vera
• Chronic neutrophilic leukemia
• Chronic myeloproliferative disease, unclassifiable
• Chronic eosinophilic leukemia
• Hypereosinophilic syndrome
• Idiopathic hypereosinophilic syndrome
• Primary hypereosinophilic syndrome
• Secondary hypereosinophilic syndrome
• Lymphocytic hypereosinophilic syndrome
• Transient myeloproliferative syndrome
• Hereditary thrombocytopenia with early-onset myelofibrosis
• Myelodysplastic/myeloproliferative disease
• Juvenile myelomonocytic leukemia
• Chronic myelomonocytic leukemia
• Atypical chronic myeloid leukemia
• Unclassified myelodysplastic/myeloproliferative disease
• Myeloid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB or FGFR1
• Myeloid neoplasm associated with PDGFRA rearrangement
• Myeloid neoplasm associated with PDGFRB rearrangement
• Myeloid neoplasm associated with FGFR1 rearrangement
• Lymphoid hemopathy
• Autoimmune lymphoproliferative syndrome
• Plasma cell tumor
• POEMS syndrome
• Multiple myeloma
• AL amyloidosis
• Primary systemic amyloidosis
• Primary localized amyloidosis
• Plasmacytoma
• Primary plasmacytoma of the bone
• Extramedullary soft tissue plasmacytoma
• Non-amyloid monoclonal immunoglobulin deposition disease
• Heavy chain deposition disease
• Light and heavy chain deposition disease
• Light chain deposition disease
• Heavy chain disease
• Mu-heavy chain disease
• Alpha-heavy chain disease
• Gamma-heavy chain disease
• Plasma cell leukemia
• Immunodeficiency-associated lymphoproliferative disease
• Post-transplant lymphoproliferative disease
• Methotrexate-associated lymphoproliferative disorders
• Lymphoproliferative disease associated with primary immune disease
• Lymphoma
• Non-Hodgkin lymphoma
• Acute lymphoblastic leukemia
• Precursor B-cell acute lymphoblastic leukemia
• Precursor T-cell acute lymphoblastic leukemia
• Mature B-cell acute lymphoblastic leukemia
• B-cell non-Hodgkin lymphoma
• Indolent B-cell non-Hodgkin lymphoma
• Follicular lymphoma
• Waldenström macroglobulinemia
• Hairy cell leukemia
• B-cell chronic lymphocytic leukemia
• Indolent primary cutaneous B-cell lymphoma
• Primary cutaneous marginal zone B-cell lymphoma
• Primary cutaneous follicle center lymphoma
• Hairy cell leukemia variant
• Marginal zone lymphoma
• MALT lymphoma
• Splenic marginal zone lymphoma
• Nodal marginal zone B-cell lymphoma
• Splenic diffuse red pulp small B-cell lymphoma
• Lymphoplasmacytic lymphoma without IgM production
• Aggressive B-cell non-Hodgkin lymphoma
• Burkitt lymphoma
• Diffuse large B-cell lymphoma
• Lymphomatoid granulomatosis
• Primary mediastinal large B-cell lymphoma
• Intravascular large B-cell lymphoma
• Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly
• Diffuse large B-cell lymphoma of the central nervous system
• T-cell/histiocyte rich large B cell lymphoma
• Diffuse large B-cell lymphoma with chronic inflammation
• ALK-positive large B-cell lymphoma
• Primary effusion lymphoma
• Mantle cell lymphoma
• B-cell prolymphocytic leukemia
• Aggressive primary cutaneous B-cell lymphoma
• Primary cutaneous diffuse large B-cell lymphoma, leg type
• Plasmablastic lymphoma
• T-cell non-Hodgkin lymphoma
• CD4+/CD56+ hematodermic neoplasm
• T-cell prolymphocytic leukemia
• T-cell large granular lymphocyte leukemia
• Aggressive NK-cell leukemia
• Adult T-cell leukemia/lymphoma
• Extranodal nasal NK/T cell lymphoma
• Enteropathy-associated T-cell lymphoma
• Hepatosplenic T-cell lymphoma
• Angioimmunoblastic T-cell lymphoma
• Anaplastic large cell lymphoma
• ALK-positive anaplastic large cell lymphoma
• ALK-negative anaplastic large cell lymphoma
• Primary cutaneous T-cell lymphoma
• Indolent primary cutaneous T-cell lymphoma
• Primary cutaneous CD30+ T-cell lymphoproliferative disease
• Lymphomatoid papulosis
• Primary cutaneous anaplastic large cell lymphoma
• Subcutaneous panniculitis-like T-cell lymphoma
• Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma
• Mycosis fungoides and variants
• Classic mycosis fungoides
• Granulomatous slack skin
• Folliculotropic mycosis fungoides
• Localized pagetoid reticulosis
• Aggressive primary cutaneous T-cell lymphoma
• Sézary syndrome
• Primary cutaneous peripheral T-cell lymphoma not otherwise specified
• Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma
• Primary cutaneous gamma/delta-positive T-cell lymphoma
• Systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease of childhood
• Hydroa vacciniforme-like lymphoma
• Peripheral T-cell lymphoma NOS
• Hodgkin lymphoma
• Classic Hodgkin lymphoma
• Classic Hodgkin lymphoma, nodular sclerosis type
• Classic Hodgkin lymphoma, mixed cellularity type
• Classic Hodgkin lymphoma, lymphocyte-rich type
• Classic Hodgkin lymphoma, lymphocyte-depleted type
• Nodular lymphocyte predominant Hodgkin lymphoma
• Composite lymphoma
• Primary organ-specific lymphoma
• Primary pulmonary lymphoma
• Primary cutaneous lymphoma
• Primary cutaneous B-cell lymphoma
• Primary central nervous system lymphoma
• Thyroid lymphoma
• Primary oculocerebral lymphoma
• Primary intraocular lymphoma
• Primary bone lymphoma
• Primary lymphoma of the conjunctiva
• RAS-associated autoimmune leukoproliferative disease
• Persistent polyclonal B-cell lymphocytosis
• Castleman disease
• Pediatric Castleman disease
• Localized Castleman disease
• Multicentric Castleman disease
• Polycythemia
• Primary familial polycythemia
• Secondary polycythemia
• Congenital secondary polycythemia
• Chuvash erythrocytosis
• Autosomal recessive secondary polycythemia not associated with VHL gene
• Autosomal dominant secondary polycythemia
• Acquired secondary polycythemia
• Gaisböck syndrome
• Rare coagulation disorder
• Rare thrombotic disease of hematologic origin
• Rare thrombotic disorder due to a coagulation factors defect
• Rare thrombotic disorder due to a constitutional coagulation factors defect
• Congenital factor XII deficiency
• Familial thrombomodulin anomalies
• Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency
• Rare hereditary thrombophilia
• Hereditary thrombophilia due to congenital protein S deficiency
• Hereditary thrombophilia due to congenital protein C deficiency
• Hereditary thrombophilia due to congenital antithrombin deficiency
• Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency
• Rare thrombotic disorder due to an acquired coagulation factors defect
• Catastrophic antiphospholipid syndrome
• Heparin-induced thrombocytopenia
• Protein S acquired deficiency
• Acquired purpura fulminans
• Simple cryoglobulinemia
• Rare thrombotic disorder due to a platelet anomaly
• Thrombotic thrombocytopenic purpura
• Congenital thrombotic thrombocytopenic purpura
• Acquired thrombotic thrombocytopenic purpura
• Rare thrombotic disorder due to a constitutional platelet anomaly
• Familial thrombocytosis
• Hereditary thrombocytosis with transverse limb defect
• Rare thrombotic disorder due to an acquired platelet anomaly
• Rare hemorrhagic disorder
• Rare hemorrhagic disorder due to a coagulation factors defect
• Rare hemorrhagic disorder due to a constitutional coagulation factors defect
• Multiple sclerosis-ichthyosis-factor VIII deficiency syndrome
• Hemophilia
• Hemophilia A
• Severe hemophilia A
• Moderately severe hemophilia A
• Mild hemophilia A
• Symptomatic form of hemophilia A in female carriers
• Hemophilia B
• Severe hemophilia B
• Moderately severe hemophilia B
• Mild hemophilia B
• Symptomatic form of hemophilia B in female carriers
• Congenital factor V deficiency
• Congenital fibrinogen deficiency
• Familial afibrinogenemia
• Familial dysfibrinogenemia
• Familial hypofibrinogenemia
• Familial hypodysfibrinogenemia
• Congenital alpha2-antiplasmin deficiency
• Congenital factor XIII deficiency
• Von Willebrand disease
• Von Willebrand disease type 1
• Von Willebrand disease type 2
• Von Willebrand disease type 2A
• Von Willebrand disease type 2B
• Von Willebrand disease type 2M
• Von Willebrand disease type 2N
• Von Willebrand disease type 3
• Congenital factor XI deficiency
• Congenital plasminogen activator inhibitor type 1 deficiency
• Congenital high-molecular-weight kininogen deficiency
• Congenital prekallikrein deficiency
• Combined deficiency of factor V and factor VIII
• Congenital vitamin K-dependent coagulation factors deficiency
• Congenital factor VII deficiency
• Congenital factor II deficiency
• Congenital factor X deficiency
• Hereditary combined deficiency of vitamin K-dependent clotting factors
• Hemorrhagic disease due to alpha-1-antitrypsin Pittsburgh mutation
• East Texas bleeding disorder
• Thrombomodulin-related bleeding disorder
• Rare hemorrhagic disorder due to an acquired coagulation factor defect
• Acquired prothrombin deficiency
• Acquired hemophilia
• Acquired von Willebrand syndrome
• Rare hemorrhagic disorder due to a platelet anomaly
• Rare hemorrhagic disorder due to a constitutional platelet anomaly
• Rare hemorrhagic disorder due to a constitutional thrombocytopenia
• Syndromic constitutional thrombocytopenia
• Stormorken-Sjaastad-Langslet syndrome
• Thrombocytopenia-absent radius syndrome
• Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome
• MYH9-related disease
• GNE myopathy
• Jacobsen syndrome
• Macrothrombocytopenia with mitral valve insufficiency
• Alpha delta granule deficiency
• Dense granule disease
• Wiskott-Aldrich syndrome
• Chédiak-Higashi syndrome
• Hereditary thrombocytopenia with normal platelets-hematological cancer predisposition syndrome
• Hermansky-Pudlak syndrome
• Hermansky-Pudlak syndrome with neutropenia
• Hermansky-Pudlak syndrome with pulmonary fibrosis
• Hermansky-Pudlak syndrome without pulmonary fibrosis
• Hermansky-Pudlak syndrome type 7
• Hermansky-Pudlak syndrome type 8
• Hermansky-Pudlak syndrome type 9
• Isolated constitutional thrombocytopenia
• Isolated hereditary giant platelet disorder
• Severe autosomal recessive macrothrombocytopenia
• Bernard-Soulier syndrome
• Thrombocytopenia with congenital dyserythropoietic anemia
• Autosomal dominant macrothrombocytopenia
• Alpha granule disease
• Gray platelet syndrome
• Quebec platelet disorder
• Medich giant platelet syndrome
• White platelet syndrome
• Paris-Trousseau thrombocytopenia
• X-linked dyserythropoetic anemia with abnormal platelets and neutropenia
• Hereditary thrombocytopenia with normal platelets
• X-linked thrombocytopenia with normal platelets
• Autosomal thrombocytopenia with normal platelets
• Congenital amegakaryocytic thrombocytopenia
• Bleeding diathesis due to thromboxane synthesis deficiency
• Isolated delta-storage pool disease
• Autosomal dominant thrombocytopenia with platelet secretion defect
• Rare hemorrhagic disorder due to a qualitative platelet defect
• Glanzmann thrombasthenia
• Cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder
• Ehlers-Danlos syndrome, fibronectinemic type
• Scott syndrome
• P2Y12 defect
• Pseudo-von Willebrand disease
• Bleeding diathesis due to a collagen receptor defect
• Bleeding diathesis due to glycoprotein VI deficiency
• Bleeding diathesis due to integrin alpha2-beta1 deficiency
• Bleeding disorder due to CalDAG-GEFI deficiency
• Rare hemorrhagic disorder due to an acquired platelet anomaly
• Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome
• TAFRO syndrome
• HELLP syndrome
• Fetal and neonatal alloimmune thrombocytopenia
• Autoimmune thrombocytopenia
• Immune thrombocytopenic purpura
• Evans syndrome
• STAT3-related early-onset multisystem autoimmune disease
• Kasabach-Merritt syndrome
• Rare anemia
• Thiamine-responsive megaloblastic anemia syndrome
• Hemoglobinopathy
• Hemoglobin E disease
• Hemoglobin D disease
• Unstable hemoglobin disease
• Alpha-thalassemia and related diseases
• Alpha-thalassemia
• Hemoglobin H disease
• Hb Bart's hydrops fetalis
• Alpha-thalassemia-related diseases
• Alpha-thalassemia-X-linked intellectual disability syndrome
• Alpha-thalassemia-intellectual disability syndrome linked to chromosome 16
• Alpha-thalassemia-myelodysplastic syndrome
• Beta-thalassemia and related diseases
• Beta-thalassemia
• Beta-thalassemia major
• Beta-thalassemia intermedia
• Dominant beta-thalassemia
• Beta-thalassemia associated with another hemoglobin anomaly
• Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome
• Delta-beta-thalassemia
• Hemoglobin C-beta-thalassemia syndrome
• Hemoglobin E-beta-thalassemia syndrome
• Hemoglobin Lepore-beta-thalassemia syndrome
• Beta-thalassemia with other manifestations
• Beta-thalassemia-X-linked thrombocytopenia syndrome
• Sickle cell disease and related diseases
• Sickle cell anemia
• Sickle cell disease associated with an other hemoglobin anomaly
• Sickle cell-beta-thalassemia disease syndrome
• Sickle cell-hemoglobin C disease syndrome
• Sickle cell-hemoglobin D disease syndrome
• Sickle cell-hemoglobin E disease syndrome
• Hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
• Hemoglobinopathy Toms River
• Hereditary methemoglobinemia
• Hemoglobin C disease
• Hemoglobin M disease
• Acquired methemoglobinemia
• Rare hemolytic anemia
• Rare constitutional hemolytic anemia
• Atypical hemolytic-uremic syndrome
• Atypical hemolytic-uremic syndrome with DGKE deficiency
• Atypical hemolytic-uremic syndrome with C3 anomaly
• Atypical hemolytic-uremic syndrome with MCP/CD46 anomaly
• Atypical hemolytic-uremic syndrome with B factor anomaly
• Atypical hemolytic-uremic syndrome with H factor anomaly
• Atypical hemolytic-uremic syndrome with I factor anomaly
• Atypical hemolytic-uremic syndrome with anti-factor H antibodies
• Atypical hemolytic-uremic syndrome with thrombomodulin anomaly
• Rare constitutional hemolytic anemia due to a red cell membrane anomaly
• Hereditary spherocytosis
• Hereditary elliptocytosis
• Distal renal tubular acidosis with anemia
• Hereditary stomatocytosis
• Overhydrated hereditary stomatocytosis
• Dehydrated hereditary stomatocytosis
• Rh deficiency syndrome
• Familial pseudohyperkalemia
• Southeast Asian ovalocytosis
• Hereditary cryohydrocytosis with reduced stomatin
• Hereditary cryohydrocytosis with normal stomatin
• Constitutional hemolytic anemia due to acanthocytosis
• Abetalipoproteinemia
• McLeod neuroacanthocytosis syndrome
• Primary CD59 deficiency
• Rare constitutional hemolytic anemia due to an enzyme disorder
• Congenital erythropoietic porphyria
• Hemolytic anemia due to hexose monophosphate shunt and glutathione metabolism anomalies
• Glutathione synthetase deficiency
• Glutathione synthetase deficiency with 5-oxoprolinuria
• Glutathione synthetase deficiency without 5-oxoprolinuria
• Gamma-glutamylcysteine synthetase deficiency
• Hemolytic anemia due to glutathione reductase deficiency
• 6-phosphogluconate dehydrogenase deficiency
• Hemolytic anemia due to a disorder of glycolytic enzymes
• Glycogen storage disease due to muscle phosphofructokinase deficiency
• Triose phosphate-isomerase deficiency
• Glycogen storage disease due to aldolase A deficiency
• Glycogen storage disease due to phosphoglycerate kinase 1 deficiency
• Hemolytic anemia due to red cell pyruvate kinase deficiency
• Hemolytic anemia due to glucophosphate isomerase deficiency
• Hemolytic anemia due to diphosphoglycerate mutase deficiency
• Non-spherocytic hemolytic anemia due to hexokinase deficiency
• Hemolytic anemia due to glyceraldehyde-3-phosphate dehydrogenase deficiency
• Class I glucose-6-phosphate dehydrogenase deficiency
• Hemolytic anemia due to an erythrocyte nucleotide metabolism disorder
• Hemolytic anemia due to pyrimidine 5' nucleotidase deficiency
• Hemolytic anemia due to adenylate kinase deficiency
• Hemolytic anemia due to erythrocyte adenosine deaminase overproduction
• Heinz body anemia
• Rare acquired hemolytic anemia
• Paroxysmal nocturnal hemoglobinuria
• Typical hemolytic-uremic syndrome
• Aplastic anemia
• Rare constitutional aplastic anemia
• Blackfan-Diamond anemia
• Dyskeratosis congenita
• Fanconi anemia
• Revesz syndrome
• Hoyeraal-Hreidarsson syndrome
• WT limb-blood syndrome
• Shwachman-Diamond syndrome
• Autosomal dominant aplasia and myelodysplasia
• Hereditary isolated aplastic anemia
• Pancytopenia-developmental delay syndrome
• Rare acquired aplastic anemia
• Idiopathic aplastic anemia
• Red cell aplasia
• Transient erythroblastopenia of childhood
• Adult pure red cell aplasia
• Monocytopenia with susceptibility to infections
• Rare deficiency anemia
• Constitutional deficiency anemia
• Constitutional megaloblastic anemia due to vitamin B12 metabolism disorder
• Methylmalonic acidemia with homocystinuria
• Methylmalonic acidemia with homocystinuria, type cblC
• Methylmalonic acidemia with homocystinuria, type cblD
• Methylmalonic acidemia with homocystinuria type cblF
• Methylmalonic acidemia with homocystinuria, type cblJ
• Methylmalonic acidemia with homocystinuria, type cblX
• Transcobalamin deficiency
• Congenital intrinsic factor deficiency
• Homocystinuria without methylmalonic aciduria
• Methylcobalamin deficiency type cblE
• Methylcobalamin deficiency type cblG
• Methylcobalamin deficiency type cblDv1
• Gräsbeck-Imerslund disease
• Constitutional megaloblastic anemia due to folate metabolism disorder
• Formiminoglutamic aciduria
• Hereditary folate malabsorption
• Constitutional megaloblastic anemia with severe neurologic disease
• Vitamin B12- and folate-independent constitutional megaloblastic anemia
• Hereditary orotic aciduria
• Hypoxanthine-guanine phosphoribosyltransferase deficiency
• Lesch-Nyhan syndrome
• Hypoxanthine guanine phosphoribosyltransferase partial deficiency
• Constitutional dyserythropoietic anemia
• Congenital dyserythropoietic anemia
• Congenital dyserythropoietic anemia type I
• Congenital dyserythropoietic anemia type III
• Congenital dyserythropoietic anemia type II
• Congenital dyserythropoietic anemia type IV
• Majeed syndrome
• Pancreatic insufficiency-anemia-hyperostosis syndrome

Service offered

• Prevention and genetic counseling
• Diagnostics
• Treatment and care

Patients covered

• Pediatrics

Department e-mail: elena.cela(ELIMINAR)@salud.madrid.org

Department phone number: +34915290037/2